In 1542 Charles V, Holy Roman Emperor, abolished slavery by decree in his Leyes Nuevas, although slavery persisted in Spain’s colonies in Puerto Rica and Cuba (until 1873 and 1886); in 1952 Agatha Christie’s murder-mystery The Mousetrap opened at the Ambassadors Theatre, London, starring Richard Attenborough and his wife Sheila Sim; in 1963 the funeral of the assassinated president John F Kennedy took place, with more than 800,000 people lining the streets to watch the procession through Washington DC; in 2016 Fidel Castro died, aged 90: he led Cuba from the 1959 revolution to 2008, defeated the CIA-sponsored Bay of Pigs invasion in 1961 and presided over the Cuban missile crisis in 1962 ( obituary, November 26, 2016).

Add 1 teaspoon of spices to your food a day since scientific research suggests this changes the composition of your gut microbiome.’ Tip three: Sleep and exerciseWe are all unique and it’s important to have the ability to recognise the micro signs your body is giving you, so you can react accordingly. For me, I know I am fatigued when my eyelids start twitching, which can be a sign of magnesium deficiency. I also get pain in my jaw. When this happens, I soak in a bath with two large cups of magnesium salts – transdermal magnesium application is so effective. It’s about getting on top of your symptoms.” Exercise Is A Double-Edged Sword Combining her personal experience, expertise and scientific research, Fix Your Fatigue focusses on the tired reader – when she was suffering, Karina found books were heavy on science and didn’t account for the fatigued mind. That’s why at the end of each chapter, a “Too Tired, Didn't Read” section summarises what the reader might have missed. And the fifth step, I think this is the most important one, is all about how you can harness the power of your brain. And that it's so important. You have to learn to manage your mind. And for me, that has been the best thing that I've done. If you're coming to Coles by car, why not take advantage of the 2 hours free parking at Sainsbury's Pioneer Square - just follow the signs for Pioneer Square as you drive into Bicester and park in the multi-storey car park above the supermarket. Come down the travelators, exit Sainsbury's, turn right and follow the pedestrianised walkway to Crown Walk and turn right - and Coles will be right in front of you. You don't need to shop in Sainsbury's to get the free parking! Where to Find Us Her clinic is increasingly busy – a pattern linked to the impacts of long Covid and workplace stresses – and Karina knew she could reach even more people through writing.

In fact, tiredness is one of your body's key ways of telling you that something isn't right, but many of us trudge through life feeling some level of fatigue or lethargy every single day. I was always unwell. I had broken sleep, headaches, pins and needles, aches and pains, tinnitus, gastrointestinal issues, dizziness and nausea.

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One of my first signs of fatigue was when I stopped sleeping well,” Karina said. “That creates quite a spiral as your mental, physical and emotional health takes a battering and you start to make poor food choices.”

We are so conditioned to over-achieve and it’s becoming almost like a badge of honour to over-work and almost celebrate tiredness and I think that’s really wrong.

When will my book be dispatched from your warehouse?

Clean up your diet and focus on nutrient density, says Karina. It’s all about adding things in, not taking anything away. Third is all about the foundational layers of well being sleep and exercise. We all need to sleep more, and exercise more, we know that.