Foo LY, Lu Y, Howell AB, Vorsa N. The structure of cranberry proanthocyanidins which inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro. Phytochemistry 2000;54:173-81. View abstract. Parry, J., Su, L., Moore, J., Cheng, Z., Luther, M., Rao, J. N., Wang, J. Y., and Yu, L. L. Chemical compositions, antioxidant capacities, and antiproliferative activities of selected fruit seed flours. J Agric Food Chem 5-31-2006;54(11):3773-3778. View abstract.

The screening visit (V0) involved obtaining informed consent, followed by collecting a fasted (>10 h) morning blood and urine sample, physical measurements (height, weight, and blood pressure). Basal blood pressure and heart rate was first collected after participants had been lying supine for 5 min, and then collected again upon standing. Participants were then provided with a standardised breakfast and underwent global cognitive screening using the Addenbrooke’s Cognitive Examination III (ACE-III). Participants were excluded if they scored <88 on the ACE-III, or had abnormal blood biochemistry, blood pressure or urine results indicative of a potential exclusion condition (e.g., diabetes, uncontrolled hypertension). Quercetin. The most abundant antioxidant polyphenol in cranberries. In fact, cranberries are among the main fruit sources of quercetin ( 6, 8, 9).In fact, cranberries are among the richest fruit sources of proanthocyanidins — especially the A-type ( 14, 20). Not all cranberry products are effective against UTIs. In fact, proanthocyanidins may be lost during processing, making them undetectable in many products ( 35). DuGan C and Cardaciotto P. Reduction of ammoniacal urinary odors by the sustained feeding of cranberry juice. J Psych Nurs 1966;4:467-470. You can use this cranberry powder as a supplement. It's worth noting that the more expensive cranberry powder supplements are really just this powder. It's just pure cranberry!

Cranberries, which are mostly carbs and fiber, contain about 90% water. They also contain vitamins and minerals like vitamin C, vitamin E, vitamin K and manganese. Gettman, M. T., Ogan, K., Brinkley, L. J., Adams-Huet, B., Pak, C. Y., and Pearle, M. S. Effect of cranberry juice consumption on urinary stone risk factors. J Urol 2005;174(2):590-594. View abstract. Nantz MP, Rowe CA, Muller C, Creasy R, Colee J, Khoo C, Percival SS. Consumption of cranberry polyphenols enhances human yo-T cell proliferation and reduces the number of symptoms associated with colds and influenza: a randomized, placebo-controlled intervention study. Nutr J 2013;12:161. doi: 10.1186/1475-2891-12-161. View abstract. Kidney stones form when certain minerals in your urine reach high concentrations. It is often very painful. Wang SY, Jiao H. Scavenging capacity of berry crops on superoxide radicals, hydrogen peroxide, hydroxyl radicals, and singlet oxygen. J Agric Food Chem 2000;48:5677-84.. View abstract.

3. What’s the Difference Between Cranberry Fruit Powder and Cranberry Juice Powder?

Bodet, C., Chandad, F., and Grenier, D. Cranberry components inhibit interleukin-6, interleukin-8, and prostaglandin E production by lipopolysaccharide-activated gingival fibroblasts. Eur J Oral Sci 2007;115(1):64-70. View abstract. Cranberries ( Vaccinium macrocarpon) are particularly rich in (poly)phenols such as anthocyanins, proanthocyanidins (both A- and B-type), flavonols and hydroxycinnamic acids ( 35), and are recognised for their antioxidant and anti-inflammatory effects ( 36– 38) along with their capacity to modulate cardiometabolic endpoints ( 38– 40). However, limited information is currently available regarding the evaluation of cranberries on cognitive performance, with the only previous study exploring the impact of cranberry intake on cognitive performance reporting no cognitive benefit of a cranberry juice consumption for 6 weeks in older adults with normal cognitive functions ( 41). A single-centre, 12-week randomised, double-blind placebo-controlled parallel study design protocol was performed. Participants attended three visits in total: a screening visit (V0), a pre-intervention baseline visit (V1), and a follow-up visit at the end of the intervention (V2). Plasma extraction of polyphenol metabolites was performed using microelution solid phase extraction (μSPE) according to validated protocols, with some modifications ( 56, 57). Briefly, plasma samples (350 μl) were diluted (1:1) with phosphoric acid 4% to reduce phenolic-protein interactions. Each sample (600 μl) was loaded on a 96 well μSPE plate, washed with water (200 μl) and 0.2% acetic acid (200 μl) and finally eluted with methanol (60 μl). The 96 well collection plates were directly put in the UHPLC autosampler for immediate analysis. Plasma samples were analysed through UHPLC DIONEX Ultimate 3000 fitted with a TSQ Vantage Triple Quadrupole Mass Spectrometer (Thermo Fisher Scientific Inc., San Jose, CA, United States) equipped with a heated-electrospray ionisation source (H-ESI-II; Thermo Fisher Scientific Inc.). Separations were performed with a Kinetex EVO C18 (100 mm × 2.1 mm), 2.6 μm particle size (Phenomenex). For UHPLC, mobile phase A was water containing 0.01% formic acid and mobile phase B was acetonitrile containing 0.01% formic acid. The gradient started with 5% B, keeping isocratic conditions for 0.5 min, reaching 95% B at 7 min, followed by 1 min at 95% B and then 4 min at the start conditions to re-equilibrate the column. The flow rate was set at 0.4 ml/min, the injection volume was 5 μl, and the column was thermostated at 40°C. The MS worked in negative ionisation mode with capillary temperature at 270°C, while the source was at 300°C. The sheath gas flow was 60 units, while auxiliary gas pressure was set to 10 units. The source voltage was 3 kV. Ultra-high-purity argon gas was used for collision-induced dissociation (CID). Compounds were monitored in

If you’re someone who struggles with UTIs, including cranberries as a part of a healthy diet is something that you can do that won’t harm you,” says O’Neill. “It could be a proactive approach.” Prevent cavities Infection by the bacterium Helicobacter pylori ( H. pylori) is considered a major cause of stomach cancer, stomach inflammation, and ulcers ( 37, 38, 39, 40). Opperman, E. A. Cranberry is not effective for the prevention or treatment of urinary tract infections in individuals with spinal cord injury. Spinal.Cord. 2010;48(6):451-456. View abstract.For example, you can make trail mix at home by using lightly salted roasted nuts and dried cranberries instead of the candy pieces you typically find in store-bought trail mix. Ansell J, McDonough M, Zhao Y, et al. The absence of an interaction between warfarin and cranberry juice: a randomized, double-blind trial. J Clin Pharmacol 2009;49:824-30. View abstract. Bailey, D. T., Dalton, C., Joseph, Daugherty F., and Tempesta, M. S. Can a concentrated cranberry extract prevent recurrent urinary tract infections in women? A pilot study. Phytomedicine 2007;14(4):237-241. View abstract. Pedersen CB, Kyle J, Jenkinson AM, et al. Effects of blueberry and cranberry juice consumption on the plasma antioxidant capacity of healthy female volunteers. Eur J Clin Nutr 2000;54:405-8. View abstract.

Even though cranberry pills are made from dried, powdered cranberries, their antioxidant content remains active. In fact, taking cranberry supplements every day for eight weeks has been shown to significantly reduce markers of oxidative stress in the body ( 23). Summary Lynch, D. M. Cranberry for prevention of urinary tract infections. Am Fam.Physician 12-1-2004;70(11):2175-2177. View abstract. It is unclear whether cranberry pills are as effective as traditional antibiotics at preventing UTIs, as studies have found conflicting results ( 11, 12). Neto, C. C., Amoroso, J. W., and Liberty, A. M. Anticancer activities of cranberry phytochemicals: an update. Mol.Nutr Food Res 2008;52 Suppl 1:S18-S27. View abstract.

Data Availability Statement

Vinson, J. A., Bose, P., Proch, J., Al Kharrat, H., and Samman, N. Cranberries and cranberry products: powerful in vitro, ex vivo, and in vivo sources of antioxidants. J Agric.Food Chem. 7-23-2008;56(14):5884-5891. View abstract. Habanova M, Holovicova M, Scepankova H, et al. Modulation of Lipid Profile and Lipoprotein Subfractions in Overweight/Obese Women at Risk of Cardiovascular Diseases through the Consumption of Apple/Berry Juice. Antioxidants 2022;11(11):2239. These mixed conclusions could be due to differences in study design or because cranberry may not be as effective at preventing the 25–35% of UTIs caused by fungi or bacteria other than E. coli ( 13, 14, 15, 16). Summary They’re most often caused by the intestinal bacterium Escherichia coli ( E. coli), which attaches itself to the inner surface of your bladder and urinary tract.