Khalaf, D., et al. (2019). The effects of oral l-arginine and l-citrulline supplementation on blood pressure. Braga, M., Gianotti, L., Radaelli, G., Vignali, A., Mari, G., Gentilini, O., and Di, Carlo, V. Perioperative immunonutrition in patients undergoing cancer surgery: results of a randomized double-blind phase 3 trial. Arch.Surg. 1999;134(4):428-433. View abstract. Also, do not give your child L-arginine unless it’s medically necessary and was suggested by a healthcare professional. Giving a child too much L-arginine is extremely dangerous and can be fatal ( 10). Is all L-arginine the same? Childress, B., Stechmiller, J. K., and Schultz, G. S. Arginine metabolites in wound fluids from pressure ulcers: a pilot study. Biol.Res Nurs. 2008;10(2):87-92. View abstract.

L-arginine is classified as a conditionally essential amino acid, meaning the body needs it in greater amounts in specific circumstances. For example, the body needs more L-arginine during infancy, pregnancy, and during critical illness ( 4). Camarena Pulido, E. E., et al. (2016). Efficacy of L-arginine for preventing preeclampsia in high-risk pregnancies: A double-blind, randomized, clinical trial [Abstract]. The most frequent adverse effects of overdosing on l-arginine include bloating, diarrhea, abdominal pain, gout, airway inflammation, low blood pressure, and more.If you’re on a plant-based diet, lentils are another great source of protein fibre, and of course arginine. Dell'Omo, G., Catapano, G., Ebel, M., Gazzano,

Berk, L., James, J., Schwartz, A., Hug, E., Mahadevan, A., Samuels, M., and Kachnic, L. A randomized, double-blind, placebo-controlled trial of a beta-hydroxyl beta-methyl butyrate, glutamine, and arginine mixture for the treatment of cancer cachexia (RTOG 0122). Support.Care Cancer 2008;16(10):1179-1188. View abstract. Bednarz, B., Wolk, R., Chamiec, T., Herbaczynska-Cedro, K., Winek, D., and Ceremuzynski, L. Effects of oral L-arginine supplementation on exercise-induced QT dispersion and exercise tolerance in stable angina pectoris. Int.J Cardiol 9-15-2000;75(2-3):205-210. View abstract. Research suggests that L-arginine supplements are generally safe for most people, even when taken in high doses of up to 30 grams per day for long periods of time. Most supplements contain only around 1-5 grams of L-arginine, so it would be difficult to take too much. Braga, M., Vignali, A., Gianotti, L., Cestari, A., Profili, M., and Carlo, V. D. Immune and nutritional effects of early enteral nutrition after major abdominal operations. Eur.J Surg. 1996;162(2):105-112. View abstract.

However, the long-term use of arginine effects on cholesterol and heart health are still yet to have any full data available. 3 What are amino acids? It also releases nitric oxide into the blood. Nitric oxide acts to widen blood vessels in the bloodstream, which may help certain circulatory conditions, according to a 2016 review. In this article you will discover the many health benefits it could have for your body. It may be hard to pronounce, but L-arginine (which sounds like ar-jen-nen) has a lot going for it.

If ED is your primary concern, you should consult a healthcare professional for more treatment options. Dosage Baligan, M., Giardina, A., Giovannini, G., Laghi, M. G., and Ambrosioni, G. [L-arginine and immunity. Study of pediatric subjects]. Minerva Pediatr 1997;49(11):537-542. View abstract. They also suggested that longer term arginine supplementation should include 1.5–2 grams of arginine per day for 4 to 7 weeks to improve aerobic performance, and 10–12 grams per day for 8 weeks to improve anaerobic performance ( 5). Chen, S., Kim, W., Henning, S. M., Carpenter, C. L., and Li, Z. Arginine and antioxidant supplement on performance in elderly male cyclists: a randomized controlled trial. J Int.Soc Sports Nutr. 2010;7:13. View abstract.While this is rare, in the cases it does occur it is often within older adults or people with medical conditions that need attention. Other names for l-arginine It’s necessary for the production of nitric oxide, a signaling molecule that’s needed for a variety of bodily processes and functions, including blood flow regulation, mitochondrial function, and cellular communication ( 1, 3). Arginine is necessary for the development of T-cells, which are white blood cells that play central roles in immune response ( 2). Blood-pressure-lowering medications: enalapril (Vasotec), losartan (Cozaar), amlodipine (Norvasc), furosemide (Lasix), etc.