Lu D, Wang D, Ip HSS, Barley F, Ramage R, She J. Measurements of polybrominated diphenyl ethers and polychlorinated biphenyls in a single drop of blood. Journal of Chromatography B. 2012; 891–892:36–43. [ PubMed] [ Google Scholar] The Conservative Blairgowrie and Glens councillor said: “We all know that in events such as this, water can come from overwhelmed drains as well as from rivers – but the amount of damage here cannot be attributed to drains. la Marca G, Villanelli F, Malvagia S, Ombrone D, Funghini S, De Gaudio M, Fallani S, Cassetta MI, Novelli A, Chiappini E. Rapid and sensitive LC-MS/MS method for the analysis of antibiotic linezolid on dried blood spot. Journal of pharmaceutical and biomedical analysis. 2012; 67:86–91. [ PubMed] [ Google Scholar] But just over a year later on Sunday, October 8, the gym and all ground floor areas – including the arena – suffered “considerable damage”. Louis GMB, Germaine M, Hediger ML, Bell EM, Kus CA, Sundaram R, McLain AC, Yeung E, Hills EA, Thoma ME. Methodology for establishing a population-based birth cohort focusing on couple fertility and children’s development, the Upstate KIDS Study. Paediatric and Perinatal Epidemiology. 2014; 28(3):191–202. [ PMC free article] [ PubMed] [ Google Scholar]

By 4pm my staff and I abandoned the venue. Obviously the team did everything they could, they tried to salvage what they could on those intervening hours and make safe electrics as best we could as well.” T1 - Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models Wimmerová S, Lancz K, Tihányi J, Šovčíková E, Kočan A, Drobná B, Palkovičová L’, Jurečková D, Fabišiková A, Čonka K. Half-lives of serum PCB congener concentrations in environmentally exposed early adolescents. Chemosphere. 2011; 82(5):687–691. [ PubMed] [ Google Scholar] Mr Cromwell said: “Unfortunately the volume of water overwhelmed the arrangements that we had in place that particular weekend.”

Olshan AF. Meeting report: the use of newborn blood spots in environmental research: opportunities and challenges. Environmental Health Perspectives. 2007; 115(12):1767–1779. [ PMC free article] [ PubMed] [ Google Scholar] An electromechanical device that works with the help of an electromagnet is called an electric bell. In a classic bell, on applying an electric current, the to and fro movement of a small hammer on a gong would produce the sound of a bell. Thus, an electric bell is an electric device generally used for signalling the presence of a guest or visitor. In July 2022, Live Active Leisure opened its state-of-the-art 100-plus station gym Bell’s Sports Centre to the public. Describing the “considerable” damage, councillor Brawn told the committee: “New gym equipment was damaged; floors to affected areas – especially the main

Valvi D, Mendez MA, Martinez D, Grimalt JO, Torrent M, Sunyer J, Vrijheid M. Prenatal concentrations of polychlorinated biphenyls, DDE, and DDT and overweight in children: a prospective birth cohort study. Environmental health perspectives. 2012; 120(3):451–457. [ PMC free article] [ PubMed] [ Google Scholar]Ma W, Kannan K, Wu Q, Bell EM, Druschel CM, Caggana M, Aldous KM. Analysis of polyfluoroalkyl substances and bisphenol A in dried blood spots by liquid chromatography tandem mass spectrometry. Analytical and Bioanalytical Chemistry. 2013a; 405:4127–4138. [ PubMed] [ Google Scholar]

DBS collected from NSP is a valuable resource for studying exposure of newborns to environmental chemicals and for studying temporal trends with exposure to environmental chemicals in newborns. In this study, a gas chromatography-high resolution mass spectrometry method with ultrasonic extraction was successfully applied for the analysis of PCBs and OCPs in DBS samples. This study presents the first evidence of temporal trends of these compounds in DBS specimens collected from newborns during the past two decades. A significant reduction in blood concentrations of PCBs and p,p′-DDE was found between 1997 and 2011. The method developed in this study is applied for a population-based birth cohort with a focus on environmental chemical exposure, couple fertility and children’s health ( Louis et al. 2014).

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Persistent organic pollutants (POPs) such as poly chlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) are bio-accumulative, toxic and susceptible to long-range atmospheric transport ( Breivik et al. 2006). Since the 1970s, the use of PCBs and several OCPs was severely restricted or banned in the United States ( Muir and Howard 2006). As a consequence, the levels of these chemicals have decreased in environmental and biological matrixes ( Sun et al. 2006; Venier and Hites 2010). However, detectable levels of PCBs and OCPs have been found in the United States’ general population ( Sjödin et al. 2014). Human exposure and adverse health effects of POPs continue to be of concern despite regulatory efforts to ban the production and use of these chemicals more than 3 decades ago in the United States ( Louis et al. 2013; Taylor et al. 2013; Wu et al. 2013). Adam BW, Alexander JR, Smith SJ, Chace DH, Loeber JG, Elvers L, Hannon WH. Recoveries of phenylalanine from two sets of dried-blood-spot reference materials: prediction from hematocrit, spot volume, and paper matrix. Clinical Chemistry. 2000; 46(1):126–128. [ PubMed] [ Google Scholar]

Covaci A, Jorens P, Jacquemyn Y, Schepens P. Distribution of PCBs and organochlorine pesticides in umbilical cord and maternal serum. Science of the total environment. 2002; 298(1):45–53. [ PubMed] [ Google Scholar] Vizcaino E, Grimalt JO, Lopez-Espinosa M-J, Llop S, Rebagliato M, Ballester F. Maternal origin and other determinants of cord serum organochlorine compound concentrations in infants from the general population. Environmental Science & Technology. 2010; 44(16):6488–6495. [ PubMed] [ Google Scholar] But Live Active Leisure board member councillor Brawn – and fellow residents who provided distressing deputations to the committee – believe the failure to close the floodgates in time was more than a contributory factor. Temporal trends of ΣPCBs (upper) and p,p′-DDE (lower) concentrations in archived dried blood spot samples from NYS newborn screening program, 1997 to 2011 Councillor Brawn explained: “As you would expect LAL [Live Active Leisure] carries the usual fully comprehensive insurance that any other commercial organisation would have. However, following severe flooding of both Bell’s and the Perth Leisure Pool in August 2020, there is an exclusion on surface water flooding.

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Suyagh MF, Iheagwaram G, Kole PL, Millership J, Collier P, Halliday H, McElnay JC. Development and validation of a dried blood spot-HPLC assay for the determination of metronidazole in neonatal whole blood samples. Analytical and Bioanalytical Chemistry. 2010; 397(2):687–693. [ PubMed] [ Google Scholar] Sjödin A, Jones RS, Focant J-F, Lapeza C, Wang RY, McGahee EE. Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United States. Environmental Health Perspectives. 2004; 112(6):654–658. [ PMC free article] [ PubMed] [ Google Scholar] Louis GMB, Sundaram R, Schisterman EF, Sweeney AM, Lynch CD, Gore-Langton RE, Maisog J, Kim S, Chen Z, Barr DB. Persistent environmental pollutants and couple fecundity: the LIFE study. Environmental Health Perspectives. 2013; 121(2):231–236. [ PMC free article] [ PubMed] [ Google Scholar] Kato K, Wanigatunga AA, Needham LL, Calafat AM. Analysis of blood spots for polyfluoroalkyl chemicals. Analytica Chimica Acta. 2009; 656(1–2):51–55. [ PubMed] [ Google Scholar]