Optibac Probiotics Bifido & Fibre - Vegan Digestive Probiotic Supplement with FOS Fibre to Maintain Regularity & 25 Billion Bacterial Cultures - 30 Sachets

Product Information

Gad M. et al (2011), ‘Regulation of the IL-10/IL-12 axis in human dendritic cells with probiotic bacteria’. FEMS Immunol Med Microbiol., 63(1) :93-107.

Akatsu, H., Iwabuchi, N., Xiao, J. Z., Matsuyama, Z., Kurihara, R., Okuda, K., Yamamoto, T., and Maruyama, M. Clinical Effects of Probiotic Bifidobacterium longum BB536 on Immune Function and Intestinal Microbiota in Elderly Patients Receiving Enteral Tube Feeding. JPEN J Parenter Enteral Nutr 11-27-2012; View abstract.Shane AL, Mody RK, Crump JA, et al. 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea. Clin Infect Dis. 2017 Oct 19. [Epub ahead of print]. View abstract. O’Mahony L, et al (2002), ‘Multi-organism comparison of probiotic performance in a murine model of Salmonella typhimurimuminfection’, Gastroenterology,122:T1337

Bairead E. el al.(2005), 'Alterations in immunological gene expression from colonic biopsies in female IBS patients following probiotic consumption'. Gastroenterology, 128(44) Foschia, M., D. P., Sensidoni, A. & Brennan, C. S. The effects of dietary fibre addition on the quality of common cereal products. Journal of Cereal Science 58, 216–227 (2013). Manzano S, De Andrés J, Castro I, Rodríguez JM, Jiménez E, Espinosa-Martos I. Safety and tolerance of three probiotic strains in healthy infants: a multi-centre randomized, double-blind, placebo-controlled trial. Benef Microbes 2017;8(4):569-578. View abstract.O’Mahony L. et al (2005), ‘Bifidobacteria induced cytokine production in vitro as predictive biomarkers of in vivo performance in the lymphocyte transfer model of IBD’, Gastroenterology,128 (4 Suppl 2):A619 As with many other strains in this database, this bacterial strain has been researched to assess its potential benefits for the relief of Irritable Bowel Syndrome (IBS) and the associated symptoms. The following studies suggest that it may do so because it has an anti-inflammatory effect in the body. It is important to note that this strain is also known by a few different names. This strain has actually recently undergone genome sequencing and whereas it was known beforehand as Bifidobacterium longum subsp. infantis35624, the genome sequencing has actually caused it to be reclassified as Bifibobacterium longum subsp. longum35634. Strictly speaking, therefore, this strain should come under the longum species however it is still much better known and commercially sold as an infantis strain, and it has been kept as such for the purpose of this Probiotics Database. This strain is also commercially known as Bifantis ®(Altmann F, et al. 2016). Bifidobacterium infantis35624 – Safety and Survival Research is conflicting, inconsistent, or weak for using B. bifidum to treat the following conditions: As some properties & benefits of probiotics may be strain-specific, this database provides even more detailed information at strain level. Read more about the strains that we have included from this genus below.

Davidson SJ, Barrett HL, Price SA, Callaway LK, Dekker Nitert M. Probiotics for preventing gestational diabetes. Cochrane Database Syst Rev. 2021;4(4):CD009951. View abstract. Konieczna P. et al (2013), ‘Portrait of an immuno-regulatory Bifidobacterium’. Gut Microbes3(3): 261-266. There are certain groups that should be cautious when taking B. bifidum. People with weakened immune systemsChang HY, Chen JH, Chang JH, Lin HC, Lin CY, Peng CC. Multiple strains probiotics appear to be the most effective probiotics in the prevention of necrotizing enterocolitis and mortality: An updated meta-analysis. PLoS One. 2017;12(2):e0171579. View abstract. O’Mahony L. et al (2005), ‘Lactobacillus and Bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles , Gastroenterology,128(3):541-51. Mohamad Nor MH, Ayob N, Mokhtar NM, et al. The effect of probiotics (MCP(®) BCMC(®) Strains) on hepatic steatosis, small intestinal mucosal immune function, and intestinal barrier in patients with non-alcoholic fatty liver disease. Nutrients 2021;13(9):3192. View abstract.

Lukasik J, Dierikx T, Besseling-van der Vaart I, de Meij T, Szajewska H; Multispecies probiotic in AAD study group. Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children: A randomized clinical trial. JAMA Pediatr 2022;176(9):860-866. View abstract. Misof, B. et al. Phylogenomics resolves the timing and pattern of insect evolution. Science 346, 763–767, doi: 10.1126/science.1257570 (2014). O'Callaghan A, van Sinderen D. Bifidobacteria and Their Role as Members of the Human Gut Microbiota. Front Microbiol. 2016 Jun 15;7:925. View abstract.Chang K., et al (2005), ‘Modulation of cytokine profiles in healthy and IBS subjects following supplementation with the unique probiotic strain, Bifidobacterium infantis35624’, P&G Health Sciences Institute Publication 2005, Gastroenterology,128, (4 Suppl 2) pp.A661 Desbonnet L. et al (2008), ‘The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat’, Journal of Psychiatric Research, 43(2):164-74. Charbonneau D.L., et al .(2005b) ‘ Fecal flora effects following oral supplementation with Bifidobacteria infantis 35624 in healthy and IBS subjects’, World Congress of Gastroenterology; September 2005; Montreal, Canada. Quinlan, A. R. & Hall, I. M. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 26, 841–842, doi: 10.1093/bioinformatics/btq033 (2010). Namba, K., Hatano, M., Yaeshima, T., Takase, M., and Suzuki, K. Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer, and cell-mediated immunity in the elderly. Biosci.Biotechnol.Biochem. 2010;74(5):939-945. View abstract.