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Furthermore, phosphatidylcholine is well-established in the medical literature for its essential role in the formation and repair of cellular membranes and contributions to overall cellular health. It also plays a significant role in metabolism, nerve signaling, and liver function. What are the Benefits of Plaquex Therapy? Given the prolonged timespan during which the extracted studies were conducted, numerous EDTA infusion regimens were used. Each infusion regimen used different minerals, EDTA salt, and EDTA dosage, resulting in a potential source of confounding for comparison between studies. Most studies (n=17) reported using Na 2EDTA as the chelating agent, with only one study using calcium Na 2EDTA. Similarly, dosage varied across studies, as some reported using a fixed EDTA dose for all patients, whereas others adjusted chelating agent dose based on body weight or glomerular filtration rate. No clear pattern emerged between EDTA dosage and patient improvement. Choice of minerals and amount of water present in the infusion may also have had a confounding effect. In studies examining renal function, a high amount of saline in the solution may have helped improve dehydrated patients, rather than EDTA chelation. Two studies that reported improved renal function did not indicate the solution components, but the improvement may have been related to the volume of crystalloid infused. TACT also suggested, in a nonprespecified analysis, that post–myocardial infarction patients with PAD as well as underlying diabetes improved significantly (HR, 0.52; P=0.0069).
Plaquex can help repair this protective layer and increase the production of natural protective substances, reducing the risk of damage to the stomach lining caused by NSAIDs. Yes, Plaquex therapy is often administered intravenously (IV) to deliver the phosphatidylcholine directly into the bloodstream. This method is used to help improve blood flow, support the repair of cell membranes, and remove plaque from blood vessels. Learn More about Other Plaquex ApplicationsPetruzzi, E. , C. Chiostri: Analisi gas-cromatografica delle varie frazioni lipidiche del siero e funzionalita piasrinica in soggetti diabetici con complicanze vascolari. 5. Nat. Congr. Ital. Soc. Diabetol., March 1974 Klemm, J. In: Phosphatidylcholine. H. Peeters (ed.) Springer: Berlin 1976, 237-243 6.Luczac, Z., R. Leutschaft. Unpublished report no. 842762 7.Pristautz, H. Munch. Med. Wschr. 117 (1975) 583-586 Hevelke, G. et al. A third study measured urinary lead and cadmium immediately pretreatment and posttreatment at baseline and after the final infusion. After the first infusion, both urinary lead and cadmium significantly increased by 22.4μg/g creatinine (SD, 15.17μg/g creatinine) and 3.0μg/g creatinine (SD, 1.59μg/g creatinine), respectively. The corresponding increases following the last infusion were 7.2μg/g creatinine (SD, 5.69μg/g creatinine) for lead and 3.4μg/g creatinine (SD, 1.94μg/g creatinine) for cadmium. Used for clogged blood vessels, out of balance blood lipids, liver issues, kidney disease, inflammatory bowel disease, cognitive decline. It’s even used for skin conditions such as Psoriasis and its core effects explain why patients look younger.
Important: Some doctors below may have begun using generic PC products. To make sure you are receiving the original Plaquex Formula, A formal study called the TACT clinical trial was a randomized controlled trial that investigated the effect of disodium EDTA chelation therapy on cardiovascular events in patients with a history of myocardial infarction (MI). Please note that these patients had all suffered a significant event already, and while chelation therapy was still shown to be beneficial, we like to see patients take a proactive approach and use chelation proactively before an event occurs. Patients 40+y with stable intermittent claudication ≥ 12mo, pain free walking distance of 50 to 200m, and ABI <0.8 in worse leg Absolutely not. Plaquex doesn't cause little pieces of plaque to break off. It works on a metabolic/biochemical level increasing LCAT, an enzyme to increase cholesterol uptake by HDL from vascular walls. Research has shown that taking phosphatidylcholine (PC), one of the main ingredients in Plaquex, can improve symptoms of psoriasis, neurodermatitis, and seborrheic eczema.
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In a trial group of Almazov et al. the mean walking distance without stopping or having to use Nitroglycerine was increased from 30-50 meters to 3000 meters. There is a close relationship between high cholesterol levels in the membranes of platelets and an increased tendency to adhesion and aggregation of platelets. 40 Deposits of platelets on vascular walls enhance the sensitivity of the wall towards substances released from platelets, increasing the wall permeability, leading to deposits of plasma constituents such as lipids in the injured wall. Plaquex, through the activation of LCAT, reduces the amount of cholesterol in the membranes of platelets, thereby reducing their tendency to adhesion and aggregation. During a 14 day trial with 500 mg PC/day given as infusions, the reactive platelet aggregation was reduced by 60%. A further study using 250mg/day over a period of 30 days in elderly patients with increased tendency to coagulation showed fibrinolytic acitivity to increase in the thrombo-elastogram. 1.5 g oral PC over 16 weeks increased serum 6-keto-PGF1, a stabilized metabolite of the antiaggregatory and vasodilatory prostaglandin PGI2 and a drop in Thromboxane levels. 49 Intervention: 500mL infusion consisting of up to 3g Na 2EDTA (adjusted downward based on estimated glomerular filtration rate, 7g ascorbic acid, 2g magnesium chloride, 100mg procaine hydrochloride, 2500U unfractionated heparin, 2mEq potassium chloride, 840mg sodium bicarbonate, 250mg pantothenic acid, 100mg thiamine, 100mg pyridoxine, sterile water)
One prospective before/after study in patients with CAD saw significant improvements in left ventricular ejection fraction. EDTA chelation for the treatment of CVD generally follows a multidose regimen of intravenous infusions in combination with oral multivitamins and minerals. An additional study (n=14), not included in this review as it did not include any health outcome, also found significant decrease in lead urine levels in patients with coronary artery disease comparing postedetate level after first and final infusions, with no significant differences found for cadmium. Serkova, V.K. Klin. Med. (Moscow) 64 (1986) 91-95 Spesivtseva, V. G. et al., Lipostabil Symposium Moscow, Nov. 1984 Kalmykova, V.I., E. B. Zakharova, Sov. Med. 4 (1989) 5-9
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These effects can subsequently contribute to subclinical changes, such as atherogenesis and hypertension, leading to clinical CVD effects. Plaquex is widely known for treating Atherosclerosis. It also reduces LDL Cholesterol and Triglyceride levels while increasing HDL Cholesterol levels.
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