BioSilk Silk Therapy Original, 355ml, White, Pack of 1

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Editor’s Note: We reviewed this article on October 31, 2023. As per our editorial policy, we are constantly updating our content, to make sure it reflects the best of the best when it comes to beauty, wellness, and fashion. We want to assure our readers that we still stand by our recommendations, which we do. Produkta apraksts. Dabīgas fiksācijas matu laka, kas piešķirs frizūrai dabīgu, noturīgu efektu. Zīda proteīni rūpējas, lai mati būtu zīdaini gludi un spīdīgi. BioSilk produkti ir bez parabēniem, bez silikoniem, bez sulfātiem (SLS, SLES). BioSilk ir unikālu inovatīvo tehnoloģiju kombinācija kopā ar dabīgā hidrolizētā zīda atjaunojošajām īpašībām! I have been using BioSilk on and off for years now. BioSilks texture is just like any other serum it is light, easy to apply on to the hair and a teeny tiny drop is good enough for the whole hair. I once used a little too much by mistake and my hair looked like I had oiled it! So, lesson is that less is definitely more with this product!

Do you know that feeling when your hair is on fleek like you’ve just got out of the salon? I love that feeling because my hair looks so smooth, soft, and has a lovely smell. Unfortunately, the effects last until you rewash your hair… Lavandas ekstrakts. Uzlabo matu struktūru, piešķir spīdumu, rūpējas par to veselīgu izskatu, padarot matus mīkstus, viegli veidojamus.Produkta apraksts. BioSilk zīda terapijas šampūns ar botāniskajiem ekstraktiem un augiem maigi attīra matus un noņem ieveidošanas pēdas, padarot tos veselīgus un pakļāvīgus. Zīda proteīns iespiežas matu struktūrā un rada neticamu spīdumu. Novērš bojājumus no veidošanas rīkiem. atdzīvina un atjauno matus, mīkstam un spīdīgam rezultātam. To begin with, I’m always trying different kinds of products for my hair. Hair masks, shampoos, conditioners, serums, etc. I have the normal type of hair, which means that I can easily deal with them. But anyway, I have one problem. My hair always looks frizzy, and it is hard to brush them after washing. Produkta apraksts. BioSilk piedāvā kondicionieri, kas piešķir matiem zīdainu, greznu mirdzumu, mati kļūst viegli ķemmējami. Bojātiem un nespodriem matiem piešķir īpašu mīkstumu. Zīda proteīni iekļūst mata iekšpusē, rūpējas par matiem, piešķirot tiem neticamu mirdzumu. On me, it works best when I use heat to style my hair. It literally transforms hair from coarse and frizzy to smooth and silky. When I dont have time to blow dry or flat iron, I put some of this on towel dried hair and tie my hair in a loose braid or put it in a bun. The result: just in a couple of hours, smooth and silky waves. This product is a compliment magnet, you can expect everyone to ooh-ah over your hair because the results are pretty amazing! Biosilk Silk Therapy Original Review

It is also one of the strongest fibers in the world equal to steel. Because of this, Farouk Shami researched and discovered the benefits of silk proteins and how they could be applied to hair. Each silk protein contained 17 of the 19 amino acids found in hair, imparting shine, taming frizz and preventing split ends. Farouk knew then that all women would want hair to be shiny, healthy looking and conditioned properly. Silk solved those three issues with one product, the magic of Silk Therapy. ExtraFlex available when paying with the HSN Card, QCard® or Zulily credit card. Select the FlexPay option above and then select ExtraFlex. Credit terms apply. Learn More Talking about the serum, it is very oily itself. So, one drop is enough for use if you have fine hair. In fact, if you use too much product on your hair, it will get greasy. What I love is its smell. It’s hard to describe it, but it smells really nice. It makes my hair bouncy and soft at the same time. As I mentioned before, it gives my hair a look as I’ve just come out of a hair salon.

Silk Therapy Original is a leave-in conditioning treatment that can be used on damp or dry hair as little or as often as needed. Personally I applied it to damp hair before blow-drying in place of all other styling products. I gave the bottle a shake (this is recommended) and worked it through the mid-lengths and ends. If you had extremely dry or frizzy hair, I think the roots would be fine, but because my strands are thin the last thing I want to do is make them greasy. Lavandas ekstrakts. Uzlabo matu struktūru, piešķir spīdumu un rūpējas par to veselīgu izskatu, padarot matus mīkstus un viegli veidojamus. Our receiving department does its best to verify and then enter the correct “Best By” dates for all incoming products. However, discrepancies do occur from time to time. This being said, the exceptionally high turnover at iHerb ensures that our inventory is among the freshest in the industry. This quest for healthier hair is how BioSilk Silk Therapy emerged in 1986. For centuries, silk was celebrated as a luxurious fabric due to its smooth texture and brilliant luster. Throughout history, silk clothed royalty and the elite, continually evolving with fashion trends to be one of the most coveted fabrics of all times. Lietošana. Nelielu daudzumu izsmidziniet uz mitriem matiem, vienmērīgi izlīdziniet pa matiem, nenomazgājiet, veidojiet kā parasti.

Produkta apraksts. Stipras fiksācijas matu laka, kas piešķirs frizūrai noturīgu efektu. Zīda proteīni rūpējas, lai mati būtu zīdaini gludi un spīdīgi. Some researchers have discussed the safety and effectiveness of microparticle scaffold prepared from silk fibroin for bone void filling ( Deshpande et al., 2022). In vitro and vivo studies showed that this scaffold was biocompatible through cytotoxicity, immunogenicity, genotoxicity, systemic toxicity, and implantation. At the same time, compared with commercial calcium-based bone gap fillers, microparticle scaffold prepared from silk fibroin is non-toxic for bone gap filling and contributes to the good healing of fracture defects. In addition, the effectiveness and safety of engineered silk fibroin and collagen tissue have been evaluated in patients with bone defects. The results showed that it is safe and effective and suggested that a larger sample of randomized controlled trials can be carried out in the next stage ( Sharafat-Vaziri et al., 2020). The latest study reported that inhalable ciprofloxacin hydrochloride microparticles (CMs) based on silk fibroin and mannitol ( Lin et al., 2021). A series of in vitro and in vivo performance evaluation tests demonstrated that CMs did not affect lung function nor induce the secretion of inflammatory cytokines in the lungs. CMs, thus would be a promising pulmonary drug delivery system for the treatment of non-cystic fibrosis bronchiectasis. All these findings revealed that silk fibroin is a kind of natural polymer material that has a prominent advantage in the application of drug carriers due to its excellent biocompatibility and biosafety. 2.3 Mechanical properties and biodegradability of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Ministry of Education, Yantai University, Yantai, China Piparmētru ekstrakts. Uzlabo matu ārējo izskatu, nostiprina matu saknes, novēršot to izkrišanu, pasargā no ātras taukainības iestāšanās. The only other ingredient worth mentioning is panthenol (or vitamin B5). Panthenol is a well-known moisturizer, so it can assist with soft, shiny manageable hair. How to Use: As a leave-in conditioning treatmentIt didn’t really seem to have any long term effects as far as hair health is concerned, but the immediate difference was palpable. If you want a simple product that will leave your strands shiny and manageable, Biosilk is a great choice. Nanotechnology can be applied to the delivery of drugs, providing a new way of cancer treatment. In the past decade, it has been found that materials that can be used as drug carriers include polyurethane functionalized starch ( Desai et al., 2021), ferritin( He et al., 2019), gold nanoparticles (AuNPs) ( Li et al., 2019), cyclodextrin ( Kang et al., 2019), and silk fibroin ( Kapoor and Kundu, 2016; Melke et al., 2016). Among them, silk fibroin, a typical natural biomaterial, exhibits versatile properties through tuning the secondary conformations and hierarchical microstructures ( Ma et al., 2020). Silk fibroin can be prepared into various drug delivery systems to meet the different requirements of cancer treatment ( Wani and Veerabhadrappa, 2018; Xu et al., 2019; Zuluaga-Vélez et al., 2021). In addition, it also has shown promising potential as a carrier in tissue repair ( Gholipourmalekabadi et al., 2020), bone defects ( Hong et al., 2020a), myocardial infarction ( Chen et al., 2018b), nerve repair ( Fernández-García et al., 2016), colitis ( Diez-Echave et al., 2021), infections ( Hassani Besheli et al., 2017), acute pancreatitis ( Hassanzadeh et al., 2021), osteoporosis ( Wang et al., 2018), and cancers ( Xie et al., 2016). At present, silk fibroin has been studied and analyzed in the field of tumor as a carrier material for drug delivery. 4.1 Breast cancer BioSilk Silk Therapy Original Serum is a restoring, weightless, leave-in treatment that reconstructs dry brittle hair. It’s infused with natural pure silk to repair, smooth and protect all hair types. BioSilk leaves your hair silky, smooth and healthy.

We are very grateful to Professor Qiang Lv of Soochow University and Dr. Muhammad Sohail of Yantai University for his professional advice. Conflict of interest Lung cancer is the most common cancer in terms of morbidity and death, thus choosing the right therapy is crucial ( Mottaghitalab et al., 2015). In recent years, silk fibroin as a carrier material to load anti-cancer drugs to treat lung cancer has also become a hot research direction. In 2014, Qu et al. used silk fibroin loaded with cisplatin to prepare a controlled-release preparation to conduct research on lung cancer cell toxicity ( Qu et al., 2014). It was found that cisplatin in the nanoparticles could be released slowly and continuously for more than 15days. Meanwhile, in vitro, anti-cancer experiments showed that silk fibroin-nanoparticles loaded with cisplatin were easily internalized by A549 lung cancer cells, transferred cisplatin to cancer cells, and then triggered apoptosis. However, these particles were not easy to be internalized by L929 mouse fibroblasts, so their inhibitory effect on the growth of normal cells was weak. The silk fibroin nanoparticles loaded with cisplatin showed a sustained and effective killing effect on tumor cells, but the inhibitory effect on normal cells was weak. This research provided a new method for preparing cisplatin-loaded silk fibroin nanoparticles and offered a new carrier system for the clinical treatment of lung cancer and other tumors. Mottaghitalab et al. also used silk fibroin as a drug carrier to load gemcitabine into a targeted nano-formulation. They explored its therapeutic effect on lung cancer in the rat model ( Mottaghitalab et al., 2017). Compared with the untargeted silk fibroin nano-formulation and the control group, the gemcitabine-targeted nano-formulation showed higher cytotoxicity, cell uptake and accumulation in lung tissue. Besides, nano-formulation targeting gemcitabine had higher potential in the treatment of induced lung tumors. In histological and radiological analysis, higher survival, lower mortality and no signs of metastasis were also observed in those animals treated with targeted agents. This study proposes an effective anti-cancer drug delivery system for targeted lung cancer. As its loaded drug, gemcitabine is limited in clinical use because it is cytotoxic. The preparation of nano-targeted formulation with silk fibroin helps to expand its use, improve the therapeutic effect, and reduce its toxic and side effects. The system may be used in the treatment of malignant lung cancer in the future. Moreover, this actively targeted nano-formulation shows a higher therapeutic effect, more aggregation effect and lower mortality in the study. This is a characteristic and advantage that untargeted nano-formulation does not have, and it also shows the advantages and potential of actively targeted nano-formulation. More interestingly, Wang et al. even found that silk fibroin peptide had a significant inhibitory effect on H460 lung cancer cells, induced the cells to arrest in the S phase, and then promoted apoptosis ( Wang et al., 2019b). Silk fibroin peptide may become a new type of therapeutic agent for lung cancer treatment. 4.4 Gastric cancer Lietošana. Nelielu daudzumu izsmidziniet uz mitriem matiem, vienmērīgi izlīdziniet pa matiem, nenomazgājiet un veidojiet kā parasti.

Bin Yu 1 † Yanli Li 1,2 † Yuxian Lin 3 Yuanying Zhu 1 Teng Hao 1 Yan Wu 1 Zheng Sun 1 Xin Yang 4* Hui Xu 1* When exogenous substances enter the body, they generally cause immunogenic reactions. However, after degumming, silk fibroin does not contain sericin, so it will not produce immunogenicity ( Florczak et al., 2021). Some studies have found that pure sericin can be used as a material with good biocompatibility, so the coexistence of silk fibroin and sericin may lead to an immune response ( Chirila et al., 2013). On the contrary, silk fibroin is a polymer that enzymes can degrade, and its degradation products also do not have immunogenicity ( Cao and Wang, 2009). Although these views are not consistent, they allow people to achieve different purposes of use by regulating the structure and performance of silk fibroin. It can be degraded by enzymes such as α-chymotrypsin, protease XIV and collagenase IA ( Sun et al., 2021). Furthermore, its degradation rate is affected by the material’s microstructure, and the degradation rate is the random structure part, silk I structure, and silk II structure in the material from fast to slow ( Umuhoza et al., 2020). Lee et al. investigated the degradation behavior of silk fibroin membranes in vitro and in vivo. They found that they were degraded in phosphate-buffered saline, medium and proteinase K solution ( Lee et al., 2012). In protease K solution, 80% of this membrane was degraded within 10days. Meanwhile, another study found also confirmed that, more importantly, its degradation products were also non-toxic and harmless ( Lu et al., 2011). Some scholars synthesized silk fibroin hydrogels through a chemical cross-linking reaction of silk fibroin ( Wu et al., 2020). By γ-ray irradiation at different doses, the chemically cross-linked silk fibroin exhibited better elasticity and better biodegradability and biocompatibility than the logistically cross-linked hydrogels. In the assay of cell proliferation, the study also evaluated the cell viability of human mesenchymal stem cells on freeze-dried silk fibroin hydrogel scaffolds. No significant cytotoxicity to human mesenchymal stem cells was observed. 3 Applications in drug delivery system Do you know that feeling when your hair is on fleek like youve just got out of the salon? I love that feeling because my hair looks so smooth, soft, and has a lovely smell. Unfortunately, the effects last until you rewash your hair