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The key to reducing the intensity of niacin flushing is to start with a low dose and gradually increase the dose over a period of weeks. Taking it with food also helps reduce the intensity of the reaction. A study shows that niacin can effectively reduce inflammation and fight harmful bacterias. Niacin treatment helps to lessen the risk of developing immune conditions such as asthma and infections. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your
If you’re looking to up your niacin intake through your diet, incorporate niacin foods into your meals regularly. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch. The other supplemental form, niacinamide, doesn’t produce flushing. However, this form isn’t effective at altering blood fats, such as cholesterol ( 3).Intake recommendations for niacin and other nutrients are provided in the Dietary Reference Intakes (DRIs) developed by an expert committee of the Food and Nutrition Board (FNB) at the National Academies of Sciences, Engineering, and Medicine [ 2]. DRI is the general term for a set of reference values used for planning and assessing nutrient intakes of healthy people. These values, which vary by age and sex, include the following:
However, one study placed mice on a high-fat diet or a control diet, and after six weeks they were given either vehicle or niacin treatments for five weeks. The researchers concluded, “Niacin treatment attenuates obesity-induced adipose tissue inflammation through increased adiponectin and anti-inflammatory cytokine expression and reduced pro-inflammatory cytokine expression in a niacin receptor-dependent manner.” ( 13) 6. Helps Treat PellagraFurthermore, it plays a role in cell signaling and making and repairing DNA, in addition to acting as an antioxidant ( 2). Deficiency Stop taking niacin or niacinamide at least two weeks before surgery. It’s possible for niacin to make allergies worse by increasing histamine levels in the body. Niacin supplements should be treated like a drug and only taken under medical supervision, since they can have side effects. SUMMARY However, high doses of niacin can cause other, more dangerous side effects, although these are rare ( 20).