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RECOMMENDED BY LEADING EYE SPECIALISTS – The AREDS2 formula is recommended by doctors and eye-care professionals because it is clinically proven. The AREDS2 research showed the benefits of nutritional support in AMD and has become the gold standard in AMD eye health. Vision Defender AMD eye supplement conforms exactly to AREDS2 recommendations so you can be confident that it works to care for your eyes and help maintain normal vision. It is thought too much cooking may destroy it. Cooking with oil or fat may help with absorption into the body. However, research is ongoing. Macushield Gold is formulated to be the exact same combination as that used in the 2nd phase of the AREDS trial. In 2011, the Selenium and Vitamin E Cancer Prevention Trial (SELECT) found a 17% increase in prostate cancer risk among men taking 400 IU of vitamin E daily for a follow-up of seven years. ( reference 10) That risk equates to 1-2 more prostate cancers per 1,000 patients who took high-dose vitamin E for one year. For unclear reasons, men who took both vitamin E and selenium did not have an increased rate of prostate cancer.
Snellen EL, Verbeek AL, et al. Neovascular age-related macular degeneration and its relationship to antioxidant intake. Acta Ophthalmol Scand. 2002 Aug;80(4):368-71. doi: 10.1034/j.1600-0420.2002.800404.x. https://pubmed.ncbi.nlm.nih.gov/12190777/ The second AREDS trial, AREDS2, looked at replacing beta-carotene with different antioxidants, lutein, and zeaxanthin. No link has been found between lung cancer and lutein and zeaxanthin for either current or ex-smokers. Chew EY, Clemons T, Sangiovanni JP, et al. The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1). Ophthalmology. 2012;119(11):2282-9. doi:10.1016/j.ophtha.2012.05.027 The trial found that people who took specific supplements were 25% less likely to progress to advanced AMD over the five-year study period.Be Proactive About Your Eye Health with VisuBright - The Comprehensive Solution for Proactive AMD Support. Lutein and zeaxanthin are yellow plant pigments which give certain foods their colour. Lutein and zeaxanthin are found in high concentrations in the macula. Another carotenoid, meso-zeaxanthin, is formed in the body from lutein. Be aware of:Supplements NOT containing standardised amounts of the active compounds anthocyanins and procyanidins, particularly if the amounts are not shown at all, as the content of the active compounds would be unknown.
Recommendations: A supplement containing lutein 10mg, zeaxanthin 2mg, and meso-zeaxanthin 10mg, and/or a supplement containing DHA/EPA omega-3. Bilberryand pine bark extractsupplements should also be considered, either on their own, or in combination with the above recommendations. Vitamin E 400 IU: Vitamin E is an antioxidant, thought to protect the eyes from damage caused by free radicals. Free radicals are unstable molecules that can cause damage to the DNA. Our comprehensive blend of vitamins and minerals, including vitamins C and E, zinc, copper, and lutein/zeaxanthin, Is expertly formulated to support your eye health, helping you maintain your vision and quality of life. Delays also often occur at Easter because the depots are shut on Easter Monday & Good Friday and hence post builds up. In the early stages of AMD, it is possible to have changes at the macula, which an optometrist or ophthalmologist can see when they examine your eye, but not have any problems with your sight.
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Research and historic use have shown both bilberry and pine bark extract supplements beneficial in eye health. Analysis of the active constituents of bilberry and pine bark and observation of the favourable effects suggests that when both are taken together, they should work in synergy to lower intraocular pressure (IOP) and hence useful in glaucoma. Multiple studies have shown that this indeed is the case [1] [2] [3]. Being natural in origin, there inevitably will be varying amounts of the beneficial compounds in bilberry and pine bark. Therefore it is important that the natural extracts are standardised. The studies showing improvement in IOP all involved a standardised extract of bilberry 80mg (standardised to 36% anthocyanins) and pine bark extract 40mg (standardised to 70% procyanidins). It is important to note that supplementation with bilberry and pine bark extract is not a replacement for conventional therapies – rather, it should be considered as a useful option to use alongside conventional therapies in the management of IOP and glaucoma. Multiple studies have shown omega-3 (DHA/EPA) supplements beneficial in reducing the prevalence and severity of dry eye disease [1] [2]. However, other studies have not found this [3]. It is worth noting that conflicting studies regarding omega-3 in other areas of health also exist, especially in the heavily researched area of cardiovascular disease. What to make of these conflicting studies? Oxidation may be a factor. DHA/EPA is commonly derived from fish oil, which is highly susceptible to oxidation. No trials have reported the oxidative state of the trial oil which would question the validity of the results and conclusions of these trials [4]. Adding antioxidants (such as vitamin E) reduce (but do not prevent) oxidation [4] [5]. Anecdotally, many people have said taking an omega-3 supplement has helped their dry eyes. Therefore it’s worth considering an omega-3 (DHA/EPA) supplement for dry eyes. While we believe that taking supplements containing lutein may be beneficial to eye health, we do not endorse any brand. Smoking Macushield Gold is recommended for those with wet macular degeneration or with signs that show they are at risk of it. Some scientists believe that another macular carotenoid, meso-zeaxanthin, is also important for macular health. It is made by the body from lutein. It was not tested in the AREDS trials and not all scientists agree on its significance. More research is needed in this area.
A healthy diet full of fruits and vegetables is thought to be beneficial in keeping our eyes as heathy as possible. Fruit and vegetables are an important source of vitamins and minerals. The NHS advises we should eat at least five portions of a variety of fruit and vegetables every day.Lippman SM, Klein EA, et al.Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA. 2009 Jan7;301(1):39-51. doi: 10.1001/jama.2008.864. Epub 2008 Dec 9. https://pubmed.ncbi.nlm.nih.gov/19066370/ Vitamin C 500 mg: Vitamin C is a vitamin that is present throughout all parts of the retina of the eye and is thought to be protective against AMD.
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