Schwabe Kaloba Pelargonium Cough and Cold Relief Tablets, 30 g

Product Information

Pelargonium sidoides are generally meant for short-term use, which is no longer than five to seven days at most. The supplements and remedies are readily available online and at many local health-food stores. The Bottom Line Evans AT, Husain S, Durairaj L, Sadowski LS, Charles-Damte M, Wang Y. Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. Lancet. 2002;359(9318):1648-1654. In single cases, signs indicating disturbances of liver function have been reported after the intake of Kaloba; the causal relationship between this effect and the use of the product has not been demonstrated. Beta-2 agonists (salbutamol syrup) did not significantly reduce the presence of cough at 7 days, or mean cough score at days 1 to 7, compared with placebo in children with acute cough or acute bronchitis (low to moderate quality evidence). There were no significant differences in adverse effects (shaking or tremor or other adverse effects) between groups (very low quality evidence).

In subgroup analysis by antibiotic, there was no significant difference in clinical improvement between doxycycline and placebo (3 RCTs), erythromycin and placebo (2 RCTs) or amoxicillin and placebo (2 RCTs; low to moderate quality evidence). However, cefuroxime significantly increased clinical improvement at follow-up in adults with acute bronchitis compared with placebo (1 RCT, n=343, 92.4% versus 79.1%; low quality evidence).Serious hypersensitivity reactions with swelling of the face, breathlessness and decrease in blood pressure. Respiratory infections like bronchitis, sinusitis, and pneumonia, tonsillitis.It is very effective for treating acute bronchitis as it increases your body’s natural healing rate. Studies have found that 40-60% of patients suffering from acute bronchitis fully resolve their symptoms within a week of Pelargonium sidoides supplementation. Some people reported experiencing benefits after just two to three days. People that are not cured after a week still experience benefits from Pelargonium sidoides supplementation, since it can treat the symptoms associated with bronchitis, including headache, fever, fatigue, cough, chest pain while coughing, sputum in the lungs, rhonchi, and nasal dripping. A 2008 report published in Phytomedicine. In their analysis of six clinical trials testing pelargonium’s efficacy as an acute bronchitis treatment, the report’s authors found that pelargonium significantly improved symptoms of acute bronchitis without causing any serious side effects.

The committee agreed that because the evidence of benefit of doxycycline over amoxicillin, clarithromycin or erythromycin is limited, these antibiotics should be offered as alternative first choices. This also reflects concerns that doxycycline is contraindicated in pregnancy, and this should be considered when choosing antibiotics for women of childbearing age. The roots of Pelargonium sidoides are soaked in water to obtain an extract for oral administration that is used as a cure for dysentery in cattle. 7. Pelargonium Sidoides Contains Healthy Metabolites In the patient information leaflet, the patient is advised to consult a doctor immediately if his or her condition does not improve within one week, in case of fever lasting for several days or in case of shortness of breath or blood in the sputum.The committee discussed the evidence that inhaled corticosteroids reduced additional treatments being sought, and they could reduce the prescribing of antibiotics for acute cough. However, any prescribed alternatives to antibiotics have workload implications as people are likely to re‑consult and expect similar treatments in the future, sending the wrong message that prescribed treatment is needed for a largely self‑limiting condition. Individuals with autoimmune diseases like rheumatoid arthritis, lupus, autoimmune hepatitis, and psoriasis should also use Pelargonium sidoides with caution as they may activate the antibodies that trigger autoimmune symptoms. Liver Damage

Linder JA, Singer DE, Stafford RS. Association between antibiotic prescribing and visit duration in adults with upper respiratory tract infections. Clin Ther. 2003;25(9):2419-2430. Paul IM, Beiler J, McMonagle A, Shaffer ML, Duda L, Berlin CM. Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents. Arch Pediatr Adolesc Med. 2007;161(12):1140-1146.

Diagnosis

Clemastine for 3 days was no more effective than placebo or chlorpheniramine in reducing cough scores in 1 RCT of children under 5 years with a common cold (very low quality evidence). Drowsiness and sleepiness was reported in 20% of children, with no difference between groups (p values not reported). P. sidoides tablets (any dosage) did not significantly reduce 'failure to resolve all symptoms' by day 7 (low quality evidence) or 'failure to resolve sputum' by day 7 (very low quality evidence) compared with placebo in children or young people with acute bronchitis. Only P. sidoides tablets of 20 mg significantly reduced 'failure to resolve cough symptoms' by day 7 (low quality evidence) compared with placebo. Liver problems including hepatitis have been reported when taking this product. However, a causal relationship has not been established. The frequency is not known. After taking this product Linder JA, Sim I. Antibiotic treatment of acute bronchitis in smokers: a systematic review. J Gen Intern Med. 2002;17(3):230-234. Antibiotics (erythromycin, cefuroxime or doxycycline) were significantly better than placebo for improving abnormal lung examination at follow-up in adults with acute bronchitis (5 RCTs, n=613, 18.5% versus 34.8%, NNT 7 [5 to 11]; moderate quality evidence). However, only 1 RCT in this analysis of cefuroxime versus placebo (accounting for 77.8% of the weight) had a significant reduction for this outcome in the antibiotic group.

Honey was well tolerated in the studies, and is readily available. However, it should not be given to children under 1 year of age because of concerns about infant botulism. It also contains sugars, and the committee discussed concerns about tooth decay.There is no particular guideline for the approximate intake of pelargonium sidoides supplements. However, the safe dosage may vary according to the severity of the disease. In addition, factors like general health, weight, sex, age and ongoing medication can influence it. Christ-Crain M, Stolz D, Bingisser R, et al. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial. Am J Respir Crit Care Med. 2006;174(1):84-93.