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Shapiro, S. and Guggenheim, B. The action of thymol on oral bacteria. Oral Microbiol.Immunol 1995;10(4):241-246. View abstract.
Thymus herba-barona (caraway thyme) is used both as a culinary herb and a ground cover, and has a very strong caraway scent due to the chemical carvone. [ citation needed]Extract preparations of common ivy ( Hedera helix L.) are widely used for the treatment of respiratory tract diseases associated with coughing [ 4, 5, 6]. Ivy for medicinal use is mainly obtained from eastern european countries. α-Hederin, one of the saponins identified in ivy leaves dried extracts, indirectly inhibits the GRK2-mediated phosphorylation of β 2AR in human airways smooth muscle (HASM) cells [ 7]. Since this phosphorylation process is required for receptor internalization, the β 2AR density on the cell surface of α-hederin treated cells is still high even under stimulation conditions. As a result, the elevated β 2-adrenergic responsiveness of α-hederin pre-treated HASM and alveolar type 2 (A549) cells was confirmed by increased β 2AR binding and enhanced cAMP-levels [ 8]. In addition to pure ivy leaves dried extract preparations, fixed fluid extract combinations of thyme herb and ivy leaves are used for the treatment of acute bronchitis and common cold with concomitant cough and viscous mucus [ 9, 10]. For a thyme extract, a comparatively weak direct interaction with β 2AR was described. In addition, an indirect modulatory effect on β 2AR was found, but the molecular mechanism was not further clarified [ 11]. Therefore, it can be assumed that α-hederin mediated inhibition of receptor internalization leads to an increased number of β 2AR, which can be activated and modulated by ingredients of the thyme fluid extract. Thus, the β 2-adrenergic signaling of an ivy/thyme combination could be superior to a pure ivy preparation. Influences of an ivy preparation and an ivy/thyme combination on the β 2AR binding and the formation of the corresponding second messenger cAMP using the same cell system have never been compared directly.
Standard care: warm alkaline mineral water, antipyretic (paracetamol), decongestant nose drops, local antibiotic (fusafungin spray) as needed b Food Storage - How Long Can You Keep Thyme". Archived from the original on 2015-08-09 . Retrieved 2015-08-18. Walker, Paul (2 September 2021). "What Is a Bouquet Garni? Easy Homemade Bouquet Garni Recipe, Plus Tips for Cooking With Bouquet Garni - 2022 - MasterClass". Masterclass . Retrieved 23 March 2022. Chesty coughs are normal accompaniments of illnesses like the common cold or influenza. They might occur as soon as symptoms present themselves and persist well beyond when a patient no longer has either virus in their system.Coughs may be a sign of worsening asthma so if your cough does not improve with treatment, speak to your doctor Kardos, P., Lehrl, S., Matthys, H., & Kamin, W. (2014, October 27). The BSS – A valid clinical instrument to measure the severity of acute bronchitis. Journal of Lung, Pulmonary & Respiratory Research, 1(3), 72–80. One open-label RCT compared an ivy/thyme preparation to standard care, defined as warm alkaline mineral water, an antipyretic (paracetamol), decongestant drops, and a local antibiotic (fusafungin) in 54 children for 7–10 days [ 18]. Outcomes included the proportion of patients with wet cough and congestion, number of daily coughing fits, fever, and laboratory markers of inflammation. The difference in coughing fits was statistically significant at treatment days 3–4 (approximately 12 vs. 18 fits/day in treatment versus standard care groups, respectively), but not at subsequent follow-up. Sakkas H, Papadopoulou C. Antimicrobial activity of Basil, Oregano and Thyme essential oils. J Microbiol Biotechnol. 2016 Dec 20. doi: 10.4014/jmb.1608.08024. [Epub ahead of print] Review. View abstract.
Park BS, Choi WS, Kim JH, et al. Monoterpenes from thyme (Thymus vulgaris) as potential mosquito repellents. J Am Mosq Control Assoc 2005;21:80-3. . View abstract. Children: Thyme is commonly consumed in foods. Thyme is possibly safe when taken as medicine for short periods of time. There isn't enough reliable information to know if thyme oil is safe to use as medicine or what the side effects might be. Klarić M, et al. (2007). Antifungal activity of thyme ( Thymus vulgaris L.) essential oil and thymol against moulds from damp dwellings.Antibiotics for viral URTIs and bronchitis are ineffective and even harmful due to potential side effects as well as the contribution to the development of bacterial resistance [ 4]. Despite widespread knowledge of the associated risks, antibiotics are frequently prescribed to patients with URTIs and bronchitis [ 5]. To combat this issue and to assist physicians in the challenge of alleviating acute cough caused by viral illnesses, a strong evidence base regarding the efficacy and safety of non-antibiotic cough remedies in adults and children is needed. Alfred Vogel recommended that walkers look out for fresh pine shoots and chew them when rambling. For those of us not out on the pine-covered hills however, it might be easier to find them in Bronchosan Cough Syrup.
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