Doctor's Best, PepZinGI, Zinc-L-Carnosine Complex, 120 Vegan Capsules, Lab Tested, Minerals, Gluten Free, SOYA Free, Vegetarian

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If you struggle with occasional digestive distress, skin issues, joint problems, mood issues, brain fog, fatigue, unhealthy cravings, or sleep problems, there’s a chance that the underlying issue may be unhealthy intestinal permeability (aka leaky gut). When the gut lining becomes weak, it allows foreign invaders to leak into your body. This can cause unwanted inflammation and a dysfunctional immune system. And that’s when things can go awry.

What’s more, glutamine is essential for supporting gut barrier integrity. Physical, mental, emotional, and environmental stress increase the body’s use of this key gut-nourishing nutrient. A meta-analysis (the gold standard of scientific evidence) found that glutamine reduced markers of increased intestinal permeability. And a research review stated that “glutamine holds great promise” in protecting the gut and for enhancing gut barrier health and function. 5,6Takaoka, T.; Sarukura, N.; Ueda, C.; Kitamura, Y.; Kalubi, B.; Toda, N.; Abe, K.; Yamamoto, S.; Takeda, N. Effects of zinc supplementation on serum zinc concentration and ratio of apo/holo-activities of angiotensin converting enzyme in patients with taste impairment. Auris Nasus Larynx 2010, 37, 190–194. [ Google Scholar] [ CrossRef] Sakae, K.; Yanagisawa, H. Oral treatment of pressure ulcers with polaprezinc (zinc L-carnosine complex): 8-week open-label trial. Biol. Trace Elem. Res. 2014, 158, 280–288. [ Google Scholar] [ CrossRef]

Authority to prescribe an Authority medicine is granted for specific indications and/or for certain patient circumstances. Authority may be obtained by telephone to Medicare Australia (known as "phone approval") or in writing from an authorised delegate of the Minister for Health. Take a look at the long list of ways increased intestinal permeability can adversely affect one’s health, well-being, and quality of life: Unlike some conventional products, PepZinGI™ provides relief of indigestion without suppressing stomach acid and possibly impacting digestive function. Different from some competitive nutritional supplements, PepZinGI™, a zinc L-carnosine complex, has also been shown to be three times more effective than zinc sulfate and L-carnosine alone. Is it safe? Gut Reg provides L-glutamine to support healthy immune system function and to support normal gut permeability.Before trying Doctor’s Best PepZin GI it is as always recommended that you consult your physician. Even though dietary supplements are sold as all-natural, it doesn’t mean that they can have adverse effect on your body. Your physician will know what is best for you. Does Doctor’s Best PepZin GI Have Side Effects? PepZin GI, a patented complex of zinc and L-carnosine, is three times more effective than either zinc or carnosine alone. 3 The gastro-protective and supportive benefits of PepZin GI have been demonstrated in over 20 published studies. These studies have shown that PepZin GI provides powerful support for the immune system to restore gut health by:

As a zinc supplement, its use is limited by safety regulations on daily zinc intake, which is about 40 mg per day for most countries. A daily intake of 150 mg PepZinGI™ is equivalent to 34 mg zinc. Baan, M.; Sherding, R.; Johnson, S. Effects of Zinc-l-Carnosine and Vitamin E on Aspirin-Induced Gastroduodenal Injury in Dogs. J. Vet. Intern. Med. 2011, 25, 39–46. [ Google Scholar] [ CrossRef] If you’re overwhelmed by that long list, I get it. I would be too, especially if you’ve been struggling for a while and feel like you’ve “tried everything.” Yoshikawa, T.; Naito, Y.; Tanigawa, T.; Yoneta, T.; Kondo, M. The antioxidant properties of a novel zinc-carnosine chelate compound, N-(3-aminopropionyl)-L-histidinato zinc. Biochim. Et Biophys. Acta BBA Gen. Subj. 1991, 1115, 15–22. [ Google Scholar] [ CrossRef]

How Can You Restore Healthy Intestinal Permeability?

McGuire, D.; Altomonte, V.; Peterson, D.; Wingard, J.; Jones, R.J.; Grochow, L. Patterns of mucositis and pain in patients receiving preparative chemotherapy and bone marrow transplantation. In Proceedings of the Oncology Nursing Forum, Orlando, FL, USA, 12–15 May 1993; pp. 1493–1502. [ Google Scholar] Shu X-L, Yu T-T, Kang K, Zhao J. Effects of glutamine on markers of intestinal inflammatory response and mucosal permeability in abdominal surgery patients: A meta-analysis. Exp Ther Med. 2016;12(6):3499-3506. doi:10.3892/etm.2016.3799

FitzGerald, A.; Murray, D.; Playford, R. Zinc carnosine is a health food supplement that stimulates both the early and later stages of gut repair. In Gastroenterology; Elsevier Inc.: Philadelphia, PA, USA, 2005; p. A219. [ Google Scholar] Maes, A.; Huygh, I.; Weltens, C.; Vandevelde, G.; Delaere, P.; Evers, G.; Van den Bogaert, W. De Gustibus: Time scale of loss and recovery of tastes caused by radiotherapy. Radiother. Oncol. 2002, 63, 195–201. [ Google Scholar] [ CrossRef]Vallee, B.L.; Falchuk, K.H. The biochemical basis of zinc physiology. Physiol. Rev. 1993, 73, 79–118. [ Google Scholar] [ CrossRef] [ PubMed]