Yves Saint Laurent Opium Homme 100ml EDT Men Spray

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Chen P, Braithwaite RA, George C, Hylands PJ, Parkin MC, Smith NW, Kicman AT: The poppy seed defense: a novel solution. Drug Test Anal. 2014 Mar;6(3):194-201. doi: 10.1002/dta.1590. Epub 2013 Dec 12. [ Article]

Meadway C, George S, Braithwaite R (August 31, 1998). "Opiate concentrations following the ingestion of poppy seed products—evidence for 'the poppy seed defence' ". Forensic Science International. 96 (1): 29–38. doi: 10.1016/S0379-0738(98)00107-8. PMID 9800363. Heroin, the first semi-synthetic opioid, was first synthesized in 1874, but was not pursued until its rediscovery in 1897 by Felix Hoffmann at the Bayer pharmaceutical company in Elberfeld, Germany. From 1898 to 1910 heroin was marketed as a non-addictive morphine substitute and cough medicine for children. Because the lethal dose of heroin was viewed as a hundred times greater than its effective dose, heroin was advertised as a safer alternative to other opioids. [104] By 1902, sales made up 5 percent of the company's profits, and "heroinism" had attracted media attention. [105] Oxycodone, a thebaine derivative similar to codeine, was introduced by Bayer in 1916 and promoted as a less-addictive analgesic. Preparations of the drug such as oxycodone with paracetamol and extended release oxycodone remain popular to this day. [ citation needed] The production methods have not significantly changed since ancient times. Through selective breeding of the Papaver somniferum plant, the content of the phenanthrene alkaloids morphine, codeine, and to a lesser extent thebaine has been greatly increased. In modern times, much of the thebaine, which often serves as the raw material for the synthesis for oxycodone, hydrocodone, hydromorphone, and other semisynthetic opiates, originates from extracting Papaver orientale or Papaver bracteatum. Garzoni, Costantino. 1840 [1573]. "Relazione dell'impero Ottomano del senatore Costantino Garzoni stato all'ambascieria di Costantinopoli nel 1573". In Le relazioni degli ambasciatori veneti al Senato, serie III, volume I, ed. Eugenio Albèri. Firenze: Clio, p. 398YSL Opium For Men is a crisp, woody oriental aftershave that combines a rich but dry blend of spices and sandlwood. YSL Opium For Men is a rich and long lasting fragrance that is an elegant and virile blend. Globally, opium has gradually been superseded by a variety of purified, semi-synthetic, and synthetic opioids with progressively stronger effects, and by other general anesthetics. This process began in 1804, when Friedrich Wilhelm Adam Sertürner first isolated morphine from the opium poppy. [100] [101] Modern vial of morphine first isolated from opium by Friedrich Sertürner This is the extract or extrait of a fragrance and represents the scent in its purest form. This often creates a smooth and round texture, which is hard to achieve with the dilution represented in the other concentrations of fragrance. The earliest clear description of the use of opium as a recreational drug in China came from Xu Boling, who wrote in 1483 that opium was "mainly used to aid masculinity, strengthen sperm and regain vigor", and that it "enhances the art of alchemists, sex and court ladies". He also described an expedition sent by the Ming dynasty Chenghua Emperor in 1483 to procure opium for a price "equal to that of gold" in Hainan, Fujian, Zhejiang, Sichuan and Shaanxi, where it is close to the western lands of Xiyu. A century later, Li Shizhen listed standard medical uses of opium in his renowned Compendium of Materia Medica (1578), but also wrote that "lay people use it for the art of sex," in particular the ability to "arrest seminal emission". This association of opium with sex continued in China until the end of the 19th century. Struempler RE: Excretion of codeine and morphine following ingestion of poppy seeds. J Anal Toxicol. 1987 May-Jun;11(3):97-9. [ Article]

The addictive character of opium is related to the binding to the μ-opioid receptors, which will activate dopaminergic neurons in the ventral tegmental area of the midbrain and thus, enhance the dopamine release in the nucleus accumbens. This mechanism involves the reward activity of the mesolimbic dopaminergic pathway. 10 Target The standard medical use of opium persisted well into the 19th century. US president William Henry Harrison was treated with opium in 1841, and in the American Civil War, the Union Army used 175,000lb (80,000kg) of opium tincture and powder and about 500,000 opium pills. [1] During this time of popularity, users called opium "God's Own Medicine". [36] Legal opium production is allowed under the United Nations Single Convention on Narcotic Drugs and other international drug treaties, subject to strict supervision by the law enforcement agencies of individual countries. The leading legal production method is the Robertson- Gregory process, whereby the entire poppy, excluding roots and leaves, is mashed and stewed in dilute acid solutions. The alkaloids are then recovered via acid-base extraction and purified. The exact date of its discovery is unknown, but it was described by Wurtz in his Dictionnaire de chimie pure et appliquée published in 1868. [135] a b c M J Brownstein (June 15, 1993). "A brief history of opiates, opioid peptides, and opioid receptors". Proceedings of the National Academy of Sciences of the United States of America. 90 (12): 5391–5393. Bibcode: 1993PNAS...90.5391B. doi: 10.1073/pnas.90.12.5391. PMC 46725. PMID 8390660.Liu HC, Ho HO, Liu RH, Yeh GC, Lin DL: Urinary excretion of morphine and codeine following the administration of single and multiple doses of opium preparations prescribed in Taiwan as "brown mixture". J Anal Toxicol. 2006 May;30(4):225-31. [ Article]

EDT’s are not as highly concentrated in oils and elixirs as an EDP or Perfume would be and contain one to three per cent of fragrance oils. This impacts the ability of the fragrance to last and around eighty percent of the oils in an EDT fragrance will evaporate within three hours of application. Creation Consumer Finance Ltd is authorised and regulated by the Financial Conduct Authority (Register no. 311518). a b c d e Brown Richard Harvey (2002). "The Opium Trade And Opium Policies In India, China, Britain, And The United States: Historical Comparisons And Theoretical Interpretations". Asian Journal of Social Science. 30 (3): 623. doi: 10.1163/156853102320945420. Max Chamka; Translated by Geraldine Ring. "3 grams of opium for 1 dollar". Caucaz europenews . Retrieved May 6, 2007. The renowned Andalusian ophthalmologic surgeon Abu al-Qasim al-Zahrawi ("Abulcasis", 936–1013 CE) relied on opium and mandrake as surgical anesthetics and wrote a treatise, al-Tasrif, that influenced medical thought well into the 16th century. [23]W. R. Martin & H. F. Fraser (September 1, 1961). "A comparative study of subjective and physiological effects of heroin and morphine administered intravenously in postaddicts". Journal of Pharmacology and Experimental Therapeutics. 133 (3): 388–399. PMID 13767429 . Retrieved June 6, 2007.